AU-KBC Research Centre,
MIT Campus of Anna University,
Chrompet, Chennai-600044.
TRAINING PROGRAMME: "DRUG DISCOVERY AND DEVELOPMENT"
17th - 20th August, 2016 (4 DAYS)
Programme Conducted by:
AU-KBC Research Centre,
MIT Campus, Chromepet,
Chennai - 600 044.
PROGRAMME BACKGROUND
To develop a new drug conventionally, one has to spend one Billion dollar and 10 –12 years time. There is no guarantee of success in this method, in spite of spending so much time and money. New methods for drug discovery and delivery are receiving considerable attention in the pharmaceutical industry. Trial-and-error discovery methods have been replaced by focused combinatorial chemistry, computer-aided drug design, and other processes. Genomics and Proteomics are complementary technologies of biological research. The potential of these technologies for biomedical revolution will be realized by integrating them into the drug discovery process at every stage from hypothesis generation to clinical evaluation. As biotechnology becomes increasingly important in drug R&D, the application of bioinformatics tools has the potential to drive growth in the worldwide pharmaceuticals drug market from the $ 1 trillion today to $1.4 trillion by 2020.The forecast value for the worldwide informatics market in the life science sector is between $1.7 and $7 billion by 2012. The modern drug discovery relies heavily on virtual research facilitated by computing power. Hardware and software companies provide an increasing variety of informatics tools for this effort.
Following on from the genomics explosion and the huge increase in the number of potential drug targets, there has been a move from the classical linear approach of drug discovery to a non-linear and high throughput approach. The field of bioinformatics has become a major part of the drug discovery pipeline playing a key role for validating drug targets. By integrating data from many inter-related yet heterogeneous resources, bioinformatics can help in our understanding of complex biological processes and help improve drug discovery.
These days, computers are an integral part of genomics-based drug discovery, helping researchers find drug targets by comparing databases of genomic information with annotations about functional information, by analyzing the data that comes in from various wet lab experiments, and by simply keeping track of the huge amounts of biological data being unearthed in life sciences research. This is the role of bioinformatics, a field that has exploded in importance over the last few years as companies have begun to realize they are drowning in raw data. But now the uses of computers for other parts of the discovery and development process are coming to the fore. Theoretically, researchers could now test virtual drug compounds against virtual protein targets, study the virtual pharmacokinetics of their optimized virtual lead in what amounts to virtual animals, study its effects on virtual organs, design a virtual clinical trial to test assumptions and variances, and even answer some regulatory questions through simulation. Somewhere in that process, a chemist has to actually mix up a compound and conduct some experiment but buckets of silicon are being added to the discovery and development process every day, with the hope that the wet lab will one day become as dry as a sand box.
TOPICS COVERED
- Translational Research for Drug Discovery
- Human Genome Project
- Target Discovery & Validation
- Lead Generation & Optimization
- Drug Discovery and Pharmacogenomics
- RNAi and Drug Discovery
- Genomic, Proteomic and Metabonomic tools in Drug Discovery & Development
- Biomarker Discovery
- Molecular Modeling & Docking
- Structure-Guided Drug Design
- Chemo informatics and Pharmacoinformatics
- Marine environment as treasure trove for Drug Source
- Natural Product Library
- Combinatorial Chemistry
- Antibiotics Resistance and Drug Discovery
- Vaccine development
- HTS for Drug Discovery
- Data Mining for Drug Discovery
- Systems Biology and Drug Discovery
Note: Please note that there won't be any wet lab experiments
AUDIENCE AND COURSE PLAN
The workshop is targeted towards Graduate and Post-graduate students in Science, Engineering and Technology / Life Science Scientists / Medicine / Pharma, Bioinformatics and Biotechnology Faculty / PhD scholars / PDF's. The presentation will be in a tutorial style and participant's interaction will be strongly encouraged.
For each topic, bird's eye view will be provided in the beginning and a list of tools and databases used also provided. Important tools in each will be demonstrated with few examples. For all categories, exercise will be given to get hands on experience. Course material will be given in the form of CD to each participant.
Course Plan
The course will be conducted in 8 sessions at the AU-KBC Research Centre, Chromepet from 17th - 20th , August 2016 (4 days; 32 hrs)
Morning Session - 09:00 AM - 01:00 PM
Afternoon Session - 02:00 PM - 06:00 PM
PAST FACULTY AND ASSOCIATES
Prof.Mukesh Doble (IIT,Chennai)
Prof.Michael Gromiha(IIT,Chennai)
Prof. P.Gautam (CBT, Anna University)
Dr. MD.Nair (Pharma Consultant,Chennai)
Dr. G.Ramesh Kumar (AU-KBC)
SCHEDULE AND REGISTRATION DETAILS
The course fee is Rs 4,950/-(Four thousand nine hundred and fifty only). Please send a Cheque / DD drawn in favour of The Director, AU-KBC Research Centrepayable at Chennai along with application duly filled.
Last Date for Registration: 14.08.2016. Please note that the number of seats is limited and registration is made on the basis of first come first served.
Participation certificate will be given at the end of the programme.
IMPORTANT NOTE: ALL THE PARTICIPANTS ARE REQUESTED TO BRING THEIR LAPTOPS.
CLICK HERE TO DOWNLOAD THE REGISTRATION FORM
CLICK HERE FOR AU KBC BIOINFORMATICS LAB
Please send your applications along with Cheque / DD to:
The Director,
AU-KBC Research Centre,
MIT Campus, Anna University Chennai, Chromepet,
Chennai - 600 044.
CONTACT:
Dr. G. Ramesh Kumar,
Course Coordinator, AU-KBC Research Centre,
MIT Campus,Anna University Chennai,Chromepet,
Chennai - 600 044.
Tel: 91-44-22232711 Extn.133,
Fax: 91-44-22232711
E-mail: grameshpub@au-kbc.org
Web site: www.au-kbc.org
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