NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS
(An Autonomous Institution of the Government of India)
P.O.: N.S.S., Kalyani 741251, West Bengal
Advertisement No. ESTB/NIBMG/2018-19/077
Applications are invited for the positions of Project Linked Persons for extramural projects to be executed by the
National lnstitute of Biomedical Genomics, Kalyani. Selected applicants will be appointed for a period of 12 months.
The tenure of appointment may be extended depending on performance and availability of funds.
Project Name & Funding Authority: Functional interrogation of interferon lambda 4 (IFN-L4) in human health and
disease; Wellcome Trust-DBT India Alliance
Project description: Under one of the aims of the project, the immunomodulatory function of human IFN-L4
(interferon lambda 4) will be investigated using the Leishmania infection model. Molecular, genetic and immunological
assays will be used to address the objectives. Expression of IFN-L4 will be examined in VL, PKDL patient samples,
healthy individuals and correlated with disease status. In other aims of the project antiviral gene expression in healthy
individuals from the Kalyani cohort will be correlated with the genetic variant that can express a functional IFN-L4;
Protein-protein interaction of IFN-L4 in mammalian cells will be screened for against a human cDNA library;
Association of severe Dengue disease with expression of human IFN-L 4 will be carried out with human samples.
Walk-in interview is being organized for recruiting
ONE (01) TECHNICIAN to conduct experiments based on
Immunological assays, infectivity assays with Leishmania parasites, ELISAs, field work in coordinating recruitment
of healthy volunteers; isolation of PBMCs, DNA/RNA isolation; qPCR, gene cloning, BiFC assay and others towards
meeting the objectives of the project.
The date of walk-in interview is Wednesday, 30th May 2018 starting from 10:30 AM. The candidates should report at
the NIBMG reception latest by 10 AM on the day of walk-in interview; those arriving later than 10 AM will not be
accommodated in the interview. The age limit is maximum 25 (twenty five) years. No TA/DA will be paid for
attending the interview.
MSc* in life
sciences
(Biochemistry,
immunology,
human genetics,
molecular
biology,
biotechnology
etc.)
Relevant work
experience in hostpathogen
interactions,
Immunological assays will
be preferred. Experience
working with Leishmania
model will also be
preferable;
Experience in
molecular cloning and
gene expression will be
desirable
Performing
immunological assays
with Leishmaniainfected
cells using
immune and molecular
phenotyping methods;
Field work involving
collection of blood
samples from the
Kalyani cohort and
processing them;
Performing gene
cloning and BiFC
assays; Genotyping
using Dengue-infected
human blood DNA and
others.
INR 20,800/-per
month
*Candidates who are awaiting degree certificates soon are also eligible to apply
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