Junior Research Fellow in a DBT India project for antimalarial drug Discovery Project on "Isolation and characterization of active antimalarial compounds from South Indian Medicinal Plants"
Project Description : This bi institutional DBT project will use state of the art activity guided HPLC purification followed by structure determination of antiplasmodial molecules derived from South Indian Medicinal Plants. Screening of plant extracts and purified molecules will be done in microtiter plate format by ex vivo culture of Plasmodium falciparum strains in human red blood cells and inhibition of growth of malaria parasite will be monitored by SYBR Green based
luorescence screen and microscopy. Selectivity Indices will be determined by comparing IC50 (Mammalian cell)/IC50 (P.falciparum).
Eligibility : Only NET/GATE qualified candidates are eligible to apply.
Further only those with good credentials in chromatography, microscopy, Spectroscopy, molecular biology, Cell Biology, diligent habits of experiment documentation and aptitude for drug discovery need apply by only by email within
two weeks to:
Dr Dinkar Sahal
Malaria Research Laboratory,
International Centre for Genetic Engineering and Biotechnology, New Delhi 110 067.
dsahal2013@gmail.com
Closing date for applications : 23 December 2013
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