helpBIOTECH Happy to Announce:
Workshop on “Protein Folding ”
23th to 25th November 2010
BIOINFORMATICS INFRASTRUCTURE FACILITY Department of Biochemistry & Biophysics
University of Kalyani Kalyani, Nadia, West Bengal
Protein folding is the physical process by which a polypeptide folds into its characteristic and functional three-dimensional structure from random coil. Amino acids interact with each other to produce a well-defined three-dimensional structure by means of the behavior of the respective amino acids and some energy functions, the folded protein, known as the native state. Failure to fold into the intended shape usually produces inactive proteins with different properties including toxic prions. Several neurodegenerative and other diseases are believed to result from the accumulation of misfolded (incorrectly folded) proteins. Many allergies are caused by the folding of the proteins, for the immune system does not produce antibodies for certain protein structures. A huge variety of unrelated diseases, such as prion diseases, diabetes and cancer, share the pathological feature of aggregated misfolded protein deposits. This suggests the exciting possibility that these 'protein-misfolding diseases' are linked by common principles, and may therefore present common targets for therapeutic intervention.
The “protein folding” consists of three closely related puzzles: (a) what is the folding code? (b) What is the folding mechanism? (c) Can we predict the native structure of a protein from its amino acid sequence? Once regarded as a grand challenge, protein folding has seen great progress in recent years. Now, foldable proteins and nonbiological polymers are being designed routinely and moving toward successful applications. The structures of small proteins are now often well predicted by computer methods. And, there is now a testable explanation for how a protein can fold so quickly: A protein solves its large global optimization problem as a series of smaller local optimization problems, growing and assembling the native structure from peptide fragments, local structures first.
The new modern science provides lots of techniques and algorithms to study protein folding both in vitro and insilico. Such methods are like Circular dichroism, Vibrational circular dichroism of proteins, Dual Polarisation Interferometry, Modeling and simulations, Folding pathway analysis. To interpret all those knowledge and with a view to introduce the subject of protein folding to the students/scientists, we are going to organize one workshop on “Protein Folding”.
Topics to be covered
Studying protein folding, Protein folding dynamics and kinetics, Thermodynamics in protein folding, Protein folding simulations and Protein folding disease.
List of tentative speakers.
1. Prof. Chanchal Kumar DasGupta IISER, Kolkata
2. Prof. Nikhil R. Pal SINP, Kolkata
3. Dr. S. Selvaraj Bharathidasan University, Tiruchirappalli
4. Prof. Anjan Dasgupta University of Calcutta, Kolkata
5. Dr. Shibasish Chowdhury BITS, Pilani
Eligibility
Faculty from Universities and affiliated colleges, Scientists and Scholars from R & D Institutes, Professionals from Industries and Biotech companies, Post-Graduates and Under-Graduate Students with biological are welcome to register for the workshop.
As the numbers of participants are limited to 20, selection will be done on the first come, first serve basis.
Procedure
The duly filled Registration Form along with the Registration fee in the form of demand draft in favour of, "University of Kalyani”, payable at “Kalyani”, should reach the coordinator, BIF Facility at the Address for Communication (Re: Contact us) by 17th November 2010. For faster, easier registration with immediate confirmation, please register online (Re: Click here ) .
Fee Structure
Type of Deligate | Registration Fees | Accommodation Fees per Day | |
| Research Scholar/Students | : | Rs. 750/- | Rs. 50 -100/- |
| Scientist/Faculty | : | Rs. 1000/- | Rs. 200/- |
| Industrial Person | : | Rs. 1500/- | Rs. 200/- |
Registration
- Last Date of Applying: 17th November 2010
- Date of Confirmation: 17th November 2010
- Workshop Date : 23rd to 25th November 2010
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