Circadian Rhythms
3. Circadian Timing Systems: How are they Organized?
Koustubh M Vaze and Vijay Kumar Sharma
Early in the course of circadian rhythm research, it became clear that individual animal subjects exhibit multiple rhythms whose peaks or troughs assume a fixed temporal relationship with each other, maintaining a state of internal synchrony.
These observations motivated enquiry into what could be the nature of the system underlying such rhythms and inspired one of the pioneer circadian biologists, Colin Pittendrigh to develop the concept of circadian organization. Pittendrigh proposed that multiple oscillators constitute circadian timing systems, and each of them regulates a different rhythm. In this article, we will discuss what the evidence over the years suggests about the circadian organization and how our understanding of
this system has matured.
Read More: www.ias.ac.in/resonance/Volumes/18/11/1032-1050.pdf
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