3rd INDIAN CANCER GENETICS CONFERENCE & WORKSHOP 2016 (An Indo-UK Program) | 7-14 December 2016

3^rd INDIAN CANCER GENETICS CONFERENCE & WORKSHOP 2016

(An Indo-UK Program)

7-14 December, 2016

 

Advanced Centre for Treatment Research & Education in Cancer (ACTREC)

Tata Memorial Centre, Navi Mumbai, India

 

PROGRAMME HIGHLIGHTS

 

7–11 December 2016: Three Parallel Hands on Training Workshops

Faculty:

 

Prof. Rajiv Sarin (Chair and Co- Convenor)

Prof. Shirley Hodgson (SVH), St George’s Hospital Medical School, London , UK

Prof. Gareth Evans, (GE), Genetic Medicine, St Mary’s Hospital, Manchester, UK

Dr. Victoria Murday (VM) Consultant Clinical Geneticist, Glasgow, Scotland, UK

Prof. Meena Upadhyaya (MU) Cardiff University, UK

Dr. Margret Ausems (MA), Consultant Cancer Geneticist, University Medical Centre Utrecht, Utrecht, The Netherlands

 

Convenor  Prof. Dhavendra Kumar, Institute of Medical Genetics, University Hospital of Wales, Cardiff University School of Medicine , UK

Chair Indo-UK Genetic Forum and Co-Convenor 

 

•       NGS (5 days 7-11^th December): Sample preparation and QC on Qubit & Bioanalyser; Library preparation for whole Exome and Transcriptome sequencing on Illumina HiSeq; Bio-informatics analysis for exome and transcriptome

 

•       Methods in Molecular Genetic Analysis (4 days 8-11^th December): Troubleshooting PCR, Different applications of PCR including methylation specific PCR, Different Genotyping techniques (CSGE, RFLP, TaqMan assay), Haplotyping, Sanger Sequencing, RT-PCR, MSI analysis, MLPA, IHC, Immunofluorescence & Tissue Microarray

 

•       Genetic counseling (4 days 8-11^th December): Counselling methods, pedigree analysis, verbal autopsies, syndrome identification, mutation probability estimation, screening algorithms & clinical management of mutation carriers

 

12-14 December 2016: Cancer Genetics Conference

 

3 day Conference with 7 international faculty from the UK and The Netherlands and 8 Indian faculty, all experts in Clinical or Molecular Cancer Genetics

Lectures, Case Based Discussions, Round Table & Role Plays will cover general and specific aspects of diverse hereditary cancers, genetic susceptibility to cancer, molecular genetic analysis from Sanger Sequencing to NGS, Interpretation of Genetic Analysis results, screening, chemoprevention and surgical prophylaxis in carriers for different gene mutations.

Registration : https://tmc.gov.in/ICGCW/

More Info :

http://www.actrec.gov.in/data%20files/Meetings/2016/Combined%20programme%20ICGCW2016.pdf

Day 1: Monday, 12^th December 2016

                               

Introduction to Inherited Predisposition to Cancer & its Molecular Basis Counselling & Indian Scenario Chairpersons: Prof. Dhavendra Kumar & Prof Rajiv Sarin
08.30-09.30	Registration and tea
09:30 -09:40	Welcome address
09:40 -10:05	Cancer Genetics & Cancer Immunology: The meeting point	Prof. Shubha Chiplunkar, ACTREC,Mumbai,India
10:05-10:30	Cancer predisposing genes - Tumour Suppressor Genes, Oncogenes & beyond	Prof. Shirley Hodgson, London and Leicester, UK
10:30 – 10:55	Inherited Predisposition to Cancer: The Indian Perspective	Prof. Rajiv Sarin,TMC Mumbai, India
10:55-11:20	Molecular Genetic analysis: Past, present and future	Dr Arindam Maitra, NIBMG, Kolkata,India
11:20–11:45	Tumour Mutations and Precision Oncology	Prof. Kumar Prabhash, TMH, Mumbai,India
11:45 – 13:00	Lunch & Poster Viewing
Breast, Ovary & Prostate Cancer:  Genetics & Risk management (screening, surgery & chemoprevention) Chairpersons:
13:00 - 13:25	Inherited Predisposition to Breast Cancer: Genetic basis; clinical manifestations; Penetrance of BRCA1/2 & other genes	Prof. Gareth Evans, Manchester, UK
13:25 - 13:50	Inherited Predisposition to Breast Cancer: Surveillance & Prophylactic Bilateral or Contralateral Mastectomy	Dr. Margreet Ausems, Utrecht, Netherlands
13:50 - 14:10	Inherited Predisposition to Breast Cancer: Chemoprevention	Dr Shona Nag,Jehangir Hospital, Pune, India
14:10 - 14:35	Inherited Predisposition to Ovarian Cancer: Genetic basis & clinical manifestations including penetrance, Surveillance & Risk Reducing Salpingo-Oopherectomy	Prof. Gareth Evans, Manchester, UK
14:35 - 15:00	Inherited Predisposition to Prostate Cancer: Genetic Testing and Risk Management	Dr. Margreet Ausems, Utrecht, Netherlands
15:00 – 15:30	Tea Break & Street Play – Genes running amock
Clinical and Laboratory Cancer Genetics Services in India              Chairperson: Prof. Lalit Kumar:
15:30 - 16:30	Genetic Testing for Cancer in India: Industry perspective	4 Private Labs (TBA)
16:30 – 17:30	Cancer Genetics Services – Report from Indian Hospitals	_ institutions (TBA)
17:30- 18:10	Establishing Cancer Genetic Services – affordable, actionable and timely testing, risk management of mutation carriers, VUS, Ethical Legal & Social issues UK faculty (2); Prof. T Rajkumar, Adyar, Prof. Lalit Kumar, Dr Sudeep Gupta, Dr Amita Maheshwari, Dr Vani Parmar, (Moderator: Rajiv Sarin)
18:15 - 18:45	General Body Meeting of the Indian Society for Cancer Genetics
19:00 – 22:00	Entertainment, Mela & Dinner in ACTREC Lawns

Day 2

Tuesday, 13th December 2016

 

DNA Repair mechanisms; Hereditary Colorectal Caners; Li-Fraumeni syndrome & XP Chairpersons
09:30 -09:55	DNA repair mechanisms & cancer: A mechanistic insight	Dr Sorab Dalal, ACTREC,Mumbai,India
09:55 – 10:20	Germline Genetic Alterations and choice of systemic therapy	Prof. T Rajkumar, Chennai,India
10:20 - 10:45	Hereditary Non-Polyposis Colon Cancer (Lynch) Syndrome: Genetic Analysis and Surveillance	Prof. Shirley Hodgson, St. Georges, London, and Leicester, UK
10:45 -11:10	Colorectal Cancers: A biologist’s perspective	Dr Murali Bhashyam,CDFD Hyderabad, India
11:10 – 11:30	Tea break
11:30 – 11:50	Polyposis Syndromes	Prof. R. Sarin, TMC,Mumbai,India
11:50 – 12:10	Prophylactic & Therapeutic surgery in FAP & Lynch Syndrome	Dr Avinish Saklani, TMC,Mumbai,India
12:10 – 12:40	Li Fraumeni syndrome & TP53	Prof. Gareth Evans, Manchester, UK
12:40 – 13:00	XP	Dr Pradnya  Kowtal, ACTREC,Mumbai,India
13:00 – 14:00	Lunch & Poster Viewing
Rare Cancer Predisposition Syndromes Chairpersons:
14:00 - 14:25	MEN syndromes	Dr. Victoria Murday, UK
14:25 - 14:50	Paraganglioma & other are endocrine tumours	Dr Nalini Shah, KEM Hospital, India
14:50- 15:15	Cowden (PTEN)	Prof. Shirley Hodgson, UK
15:15 - 15:40	Tuberous Sclerosis & Gorlin Syndrome	Prof. Gareth Evans,UK
15:40 - 16:05	VHL & inherited renal cancers	Dr. Victoria Murday,UK
16:05 – 16:25	Tea break
16:25 -17:30	SS Agarwal Oration: (Chairpersons: Prof. S. Chiplunkar / Dr MG Deo
	“Our Footprints on the Sands of Time”	Prof. Partha Majumder,NIBMG Kolkata,India
19:00 – 22:00 Hrs Dinner

 

Day 3

Wednesday, 14th December 2016

 

Inherited Childhood Cancer Predisposition   Chairperson:
09:30 - 09:50	Histopathological features indicating underlying genetic alterations	Dr Poonam Gera, ACTREC, Mumbai
09:50 - 10:10	Clinical Genetic Approach to Pediatric Tumours	Prof. Dhavendra Kumar, Cardiff, UK
10:10 – 10:30	Retinoblastoma	Dr Girish Chinnaswamy, TMH, Mumbai India
10:10 – 10:30	RAS / MAP Kinase Pathway Syndromes	Prof. Meena Upadhyaya, Cardiff, UK
10:30 – 10:50	NF1 and NF2	Prof. Gareth Evans, UK
10:50 - 11:10	Tea Break
11:10 - 11:30	Prenatal and Preconception genetic diagnosis	Dr Parag Tamhankar, NIRRH, Mumbai
11:30-12:10	Role play followed by case based discussion on issues in genetic testing including prenatal testing, clinical management and cancer prevention in children	Tushar Vora, Tejpal Gupta, Banavali, dr Agarwal (Genepath), UK
12:10:12:30	Pharmacogenomics in modern medicine	Dr Vikram Gota, ACTREC, Mumbai
12:30-12:50	The Global BRCA Challenge	Prof. Dhavendra Kumar
12:50-13:40	LUNCH
13:40-14:40	Debate for and against “Personalized Genomic - Hope or Hype”
14:40 – 15:30	Oral presentations	5 presentations
15:30 – 16:30	Best Paper Session	6 presentations
16:30 – 17:00	Participant Feedback, awards & closing Remarks