Chrm1 & Chrm3 | Researchers Identify 2 Genes that Control REM Sleep

An international group of scientists from Japan and Australia has identified two essential genes involved in the regulation of rapid eye movement (REM) sleep.


Sleep is a universal and vital behavior in animals. In higher vertebrates such as mammals and birds, sleep is classified into two phases, REM sleep and non-REM sleep.

In the new study on mice, scientific team found that two acetylcholine receptor genes — Chrm1 and Chrm3 (cholinergic receptor muscarinic 1 and 3) — are essential for REM sleep.

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