JRF Position in
Bioinformatics – Molecular Dynamics Simulations
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Project
Title
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Investigating the effect of Osmolytes on the Interplay of
Dynamics of Water, protein and DNA: Implications for Modulating Protein-DNA
Specificity
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Funding
Agency
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Department of Biotechnology, Government of India
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Duration
of Project
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2018
– 2021
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Fellowship
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As
per rules and regulations
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Essential
qualification
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First class in M. Sc. or M. Tech. (Biophysics, Bioinformatics,
Biotechnology, Physics, or related fields)
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Project
Description
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Engineering the specificity in protein-DNA interactions has
immense therapeutic potential. However, a rational guideline to engineering
specificity has been elusive till-date primarily because of the lack of
fundamental understanding of the interplay between various factors
contributing to protein-DNA interactions. This project aims at understanding
the interplay of water and protein dynamics towards specificity in
protein-DNA interactions. The project will employ computational methods
(molecular dynamics simulations) to address the research question.
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Interested candidates may send their
latest resume by email to Dr. Vigneshwar Ramakrishnan (vignesh@scbt.sastra.edu) on or before 25 December
2018. Date of test and interview will be notified by email to
selected candidates later. No TA/DA will be paid for appearing in the
interview.
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