SASTRA JRF Position in Biotechnology/Molecular Biology/Stem Cell Biology

JRF Position in Biotechnology/Molecular Biology/Stem cell Biology–Allogenic Mesenchymal Stem cells for Bone Regeneration 

Project Title Unraveling the Molecular Mechanism(s) Behind the Immune-switch from Immunosuppressive to Immunogenic Phenotype in Differentiated Allogenic Mesenchymal Stem Cells Intended for Bone Tissue Repair/Regeneration

Funding Agency Department of Science & Technology- Science and Engineering Research Board, Government of India

Fellowship As per project norms

Essential qualification First class in M. Sc. or M. Tech. (Biotechnology/Molecular Biology/Life Sciences/any related field).

Desirable: CSIR-UGC NET/GATE qualification.

Project Description Allogenic Mesenchymal stem cells are immunoprivileged and widely explored for bone regeneration applications. But following transplantation it converts to an immunogenic phenotype and gets rejected. This project will delineate the following questions (a) What is the immune status of stem cells upon osteo differentiation and under hypoxic environment? and (b) What is the status of molecular mechanism(s) responsible for maintaining immunoprivilege under these conditions. This project will mainly involve isolating rat bone marrow derived mesenchymal stem cells and answering the above questions in vitro by using modern molecular biology tools.

Interested candidates may send their latest resume by email to Dr. Saravanan Sekaran ( on or before 20 October 2019. 

Shortlisted candidates will have to appear for a test and interview. 

The date of the test and interview will be notified by email only to the shortlisted candidates. No TA/DA will be paid for appearing in the interview.

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