Job Description
Job Opening TL-11 (applicants must list this number in their application to be considered)
Senior Research Scientist in Stem Cell Biology and Disease Modeling at TIGS
Tata Institute for Genetics and Society (TIGS-CI), is a new, non-profit research entity supported by the Tata
Trusts. TIGS has been operational since 2018 as an autonomous Centre at in Stem (TIGS-CI), within the campus
of the National Center for Biological Sciences (NCBS), in Bengaluru, India. Research at TIGS is focused on
harnessing new genetic technologies, such as genome editing for improvements in human health and agriculture.
Specific areas of focus are vector-borne diseases, rice genetics, human haematopoietic stem cells (HSCs) and
reversal of antibiotic resistance. TIGS also partners actively with a sister institute located at the University of
California, San Diego (TIGS-UCSD) for scientific exchange and capacity building.
TIGS-CI is seeking applications from outstanding candidates for the position of Senior Research Scientist
(equivalent to an Assistant Professor at excellent academic institutions) to direct research in human HSC biology
to model and correct genetic disorders. This includes the identification and characterization of haematopoietic
disorders for therapeutic application of genome and base editing, as well as contributions to regulatory and
community engagement processes. The position is for a 5-year inaugural term and the incumbent is expected to
work in Bengaluru at TIGS-CI.
Senior Research Scientist in Stem Cell Biology and Disease Modelling at TIGS
This candidate will be personally engaged in, and supervise, a small team of less than 5 individuals, in the areas
of HSC propagation and differentiation, will have a proven track-record evidenced by publications in genome
editing of stem cells to generate and/or correct disease models, and possess expertise in HSC biology.
Candidates may be from a basic research or clinical background. The team will work to generate disease models,
build and test new genome editing constructs, establish human HSC cultures from embryonic stem cells or
induced pluripotent stem cells, from patient samples and test applications of genome and base editing to achieve
disease correction in human HSC. This individual will also work closely with other genome editing and active
genetics groups at TIGS to integrate new advances in this area.
Essential qualifications/requirements
The successful candidate should have a Ph.D., or equivalent, with 5+ productive years (post Ph.D.) of
academia/clinical research/industry experience in a relevant field (e.g. stem cell biology, haematopoiesis, blood
disorders, genome and base editing). Individuals transitioning from academia would preferably hold, or be eligible
for, the rank of Assistant Professor in an internationally reputed university or research institute. Additional
requirements include an outstanding track record of independence and leadership, peer-reviewed publications in
high impact journals, excellent communication skills, as well as evidence of independent grant support, project
implementation and successful mentoring of students.
TIGS-CI offers world class research facilities, including a new stem cell laboratory, and is located in an excellent
academic environment within a collaborative ecosystem, involving in Stem, NCBS, CCAMP and the Bangalore
Life Sciences Cluster (BLiSc). TIGS offers a competitive salary and benefits package and research support for
projects directly related to the TIGS mission, but all scientists are also encouraged to apply for external grants.
Applications are encouraged from both national and international scholars. The successful candidate will
collaborate closely with researchers at TIGS-CI and TIGS-UCSD to implement the TIGS mission in a sociallyconscious and ethical manner.
For consideration of your application, please provide the following documents – (a) a two-page statement
of purpose explaining the salient aspects of your background that are relevant to the position; (b) your curriculum
vitae with a list of peer-reviewed publications, and names and contact details for at least 3 references; (c)
leadership qualifications; (d) previous grant support as the principal or co-principal investigator, and (e) a list of
students mentored. Incomplete applications will not be considered. Please send the materials, with a clear
reference to the job number listed above, to the following email address: jobs@tigs.res.in.
Application deadline: 29 February 2020.
The position will remain open till it is filled.
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