INSTITUTE F OR STEM CELL SCIENCE AND REGENERATIVE MEDICINE
(an Autonomous Institute of the Department of Biotechnology)
GKVK Campus, Bellary Road,
Bangalore-560065
ADVERTISEMENT NO. inStem/10/2020
The Institute for Stem Cell Science and Regenerative Medicine (inStem, www.instem.res.in), an
Autonomous Institute of the Department of Biotechnology, Government of India, invites online applications
from eligible and interested candidates under Scientific Cadre for Fellow-E (Scientist-D) to work as Head
Mouse Genome Engineering Facility (MGEF) at Bangalore Life Science Cluster on Direct Recruitment
failing which by Deputation/ Absorption.
IMPORTANT NOTE: Only online applications will be accepted. Applications received through
any other mode shall stand rejected automatically.
ABOUT THE POST:
inStem is seeking a facility in charge to manage the Mouse Genome Engineering Facility (MGEF). The
MGEF is established with the following objectives:
Support the generation of novel genetically engineered mouse models for campus laboratories
as well as external clientele
Offer cryopreservation and cryo-recovery/mouse IVF services
Manage cryopreserved stocks and establish and maintain a mouse cryobank
Organize training and hands-on workshops on mouse embryology, cryopreservation and IVF
techniques as well as on the different types of mouse transgenesis/ knockin/ knockout/
knockdown techniques
Crispr/cas gene editing, molecular biology, cloning, qRT-PCR, Transgenic mouse genotyping.
Handling Laboratory Mice and maintaining Transgenic mouse colonies according to Laboratory
Animal Ethical Standards and guidelines.
Embryo & Sperm Cryopreservation, In Vitro Fertilization, embryo transfer into pseudo pregnant
foster females and Assisted Reproductive technologies.
The incumbent of this position will also be a key member of the senior management staff for the
Animal Care and Resource Centre (ACRC) whose mandate is to provide services and resources for
investigators to accomplish animal research goals. The candidate should have significant experience
in the area of (mouse) genome engineering. Experience in a facility setting including the handling of
capital budgets in an academic or industry setting would be an added advantage.
The services provided by the ACRC include, but is not limited to, the acquisition and housing of
laboratory animals, training researchers regarding proper animal care and use, maintaining and
operating state-of-the art facilities, and monitoring the safety of all personnel with laboratory animal
contact. Importantly, the ACRC is dedicated to ensuring the humane and ethical usage of animals
for research pursuits by strictly complying with the CPCSEA (Committee for the Purpose of Control
and Supervision of Experiments on Animals) and in-house animal care principles, rules, regulations
and guidelines. More information about the ACRC can be found at:
https://www.instem.res.in/research-facilities/acrc.
Key responsibilities of the selected candidate will include:
Coordinating & supervising all Mouse novel genome engineering projects, mouse stock
cryopreservation and rederivation projects with internal and external clients.
Coordination with faculty, administration and finance to ensure proper function of the facility &
managing Facility accounts & budgets.
Assist with grant writing and search of additional resources to maintain and expand facility
operations.
Discuss and implement the decisions taken by the Facility Faculty Advisory Committee
Developing novel procedures to develop and maintain laboratory animal resources and maintain the
national mouse repository.
Ensuring proper maintenance of all the Specific Pathogen Free Animal Colonies required for all
Mouse Genome Engineering related procedures and technologies.
Designing and coordinating workshops and training programs for internal and external scientist on
Mouse Genome Engineering, MicroInjection, stock cryopreservation and in assisted reproductive
technologies (ARTs).
Transmit training in Crispr/cas gene editing, molecular biology, cloning, qRT-PCR, Transgenic
mouse genotyping, embryo & Sperm Cryopreservation, In Vitro Fertilization, embryo transfer into
pseudo pregnant foster females and Assisted Reproductive technologies. mouse embryo microinjection techniques
Maintaining financial accounts
Writing and maintaining Facility Standard Operative Procedures.
Training new staff
COMPENSATION/ PAY DETAILS:
The post carries the pay level-12 (Starting Basic Pay Rs. 78,800/-) in the pay structure of 7th CPC Pay
Matrix and other benefits which include Dearness Allowance, House Rent Allowance (in lieu of
accommodation), Transport Allowance, Children Education Allowance, Leave Travel Concession,
Medical Facilities as per Govt. of India Rules. The selected candidate will be covered under National
Pension System (NPS).
Essential Qualification & Experience
Masters in Life Sciences/Medicine or equivalent, with 5 years’ experience.
Desirable:
Ph.D in Life Sciences or other Allied Sciences.
Should be an outstanding scientist with a strong and exceptional research
record and intentions of collaborative/ thematic research.
Should have a strong research record with promise to contribute to the focused
research themes at the institute and/or carry out their own discovery driven
research experience in the relevant field with ability to foster interactions
among basic scientists and clinicians.
Experience for Deputation:
Scientists from Central/State Governments, Research Institutes
Autonomous Bodies etc.
(i) Holding analogous post on regular basis in parent Department or
(ii) With 4 years’ service in Level- 11 or equivalent in the parent cadre/
Department and possess the essential qualification & experience
as mentioned above.
Note:
InStem is a premiere organization under the Department of Biotechnology, Government of India and
its mandate is world class research. The institute is looking for Applicants with requisite capabilities,
skills, qualifications, aptitude, merit and suitability to fulfil the institute’s objectives. Merely meeting
minimum eligibility criteria will not automatically entitle a candidate to be called for assessment. The
prospective applicants should align with the requirements of a scientific and research institute and
willing to work in a competitive environment with full enthusiasm and dedication.
It may be noted that candidature will remain provisional till the veracity of the concerned documents
are verified by the Appointing Authority.
Qualification and experience in the relevant field alone will be considered
More Info: https://www.instem.res.in/jobportal/
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