Head Mouse Genome Engineering Facility (MGEF) Scientist Job Opening

(an Autonomous Institute of the Department of Biotechnology) 
GKVK Campus, Bellary Road, 

ADVERTISEMENT NO. inStem/10/2020 

The Institute for Stem Cell Science and Regenerative Medicine (inStem, www.instem.res.in), an Autonomous Institute of the Department of Biotechnology, Government of India, invites online applications from eligible and interested candidates under Scientific Cadre for Fellow-E (Scientist-D) to work as Head Mouse Genome Engineering Facility (MGEF) at Bangalore Life Science Cluster on Direct Recruitment failing which by Deputation/ Absorption. 

IMPORTANT NOTE: Only online applications will be accepted. Applications received through any other mode shall stand rejected automatically. 

ABOUT THE POST: inStem is seeking a facility in charge to manage the Mouse Genome Engineering Facility (MGEF). The MGEF is established with the following objectives: 
 Support the generation of novel genetically engineered mouse models for campus laboratories as well as external clientele 
 Offer cryopreservation and cryo-recovery/mouse IVF services 
 Manage cryopreserved stocks and establish and maintain a mouse cryobank 
 Organize training and hands-on workshops on mouse embryology, cryopreservation and IVF techniques as well as on the different types of mouse transgenesis/ knockin/ knockout/ knockdown techniques 
 Crispr/cas gene editing, molecular biology, cloning, qRT-PCR, Transgenic mouse genotyping. 
 Handling Laboratory Mice and maintaining Transgenic mouse colonies according to Laboratory Animal Ethical Standards and guidelines. 
 Embryo & Sperm Cryopreservation, In Vitro Fertilization, embryo transfer into pseudo pregnant foster females and Assisted Reproductive technologies.

The incumbent of this position will also be a key member of the senior management staff for the Animal Care and Resource Centre (ACRC) whose mandate is to provide services and resources for investigators to accomplish animal research goals. The candidate should have significant experience in the area of (mouse) genome engineering. Experience in a facility setting including the handling of capital budgets in an academic or industry setting would be an added advantage. 

The services provided by the ACRC include, but is not limited to, the acquisition and housing of laboratory animals, training researchers regarding proper animal care and use, maintaining and operating state-of-the art facilities, and monitoring the safety of all personnel with laboratory animal contact. Importantly, the ACRC is dedicated to ensuring the humane and ethical usage of animals for research pursuits by strictly complying with the CPCSEA (Committee for the Purpose of Control and Supervision of Experiments on Animals) and in-house animal care principles, rules, regulations and guidelines. More information about the ACRC can be found at: https://www.instem.res.in/research-facilities/acrc

Key responsibilities of the selected candidate will include: 

 Coordinating & supervising all Mouse novel genome engineering projects, mouse stock cryopreservation and rederivation projects with internal and external clients. 
 Coordination with faculty, administration and finance to ensure proper function of the facility & managing Facility accounts & budgets. 
 Assist with grant writing and search of additional resources to maintain and expand facility operations. 
 Discuss and implement the decisions taken by the Facility Faculty Advisory Committee 
 Developing novel procedures to develop and maintain laboratory animal resources and maintain the national mouse repository. 
 Ensuring proper maintenance of all the Specific Pathogen Free Animal Colonies required for all Mouse Genome Engineering related procedures and technologies. 
 Designing and coordinating workshops and training programs for internal and external scientist on Mouse Genome Engineering, MicroInjection, stock cryopreservation and in assisted reproductive technologies (ARTs). 
 Transmit training in Crispr/cas gene editing, molecular biology, cloning, qRT-PCR, Transgenic mouse genotyping, embryo & Sperm Cryopreservation, In Vitro Fertilization, embryo transfer into pseudo pregnant foster females and Assisted Reproductive technologies. mouse embryo microinjection techniques 
 Maintaining financial accounts  Writing and maintaining Facility Standard Operative Procedures. 
 Training new staff 

COMPENSATION/ PAY DETAILS: The post carries the pay level-12 (Starting Basic Pay Rs. 78,800/-) in the pay structure of 7th CPC Pay Matrix and other benefits which include Dearness Allowance, House Rent Allowance (in lieu of accommodation), Transport Allowance, Children Education Allowance, Leave Travel Concession, Medical Facilities as per Govt. of India Rules. The selected candidate will be covered under National Pension System (NPS). 

Essential Qualification & Experience Masters in Life Sciences/Medicine or equivalent, with 5 years’ experience. 

Desirable: Ph.D in Life Sciences or other Allied Sciences. Should be an outstanding scientist with a strong and exceptional research record and intentions of collaborative/ thematic research. Should have a strong research record with promise to contribute to the focused research themes at the institute and/or carry out their own discovery driven research experience in the relevant field with ability to foster interactions among basic scientists and clinicians. 

Experience for Deputation: Scientists from Central/State Governments, Research Institutes Autonomous Bodies etc. (i) Holding analogous post on regular basis in parent Department or (ii) With 4 years’ service in Level- 11 or equivalent in the parent cadre/ Department and possess the essential qualification & experience as mentioned above. 


 InStem is a premiere organization under the Department of Biotechnology, Government of India and its mandate is world class research. The institute is looking for Applicants with requisite capabilities, skills, qualifications, aptitude, merit and suitability to fulfil the institute’s objectives. Merely meeting minimum eligibility criteria will not automatically entitle a candidate to be called for assessment. The prospective applicants should align with the requirements of a scientific and research institute and willing to work in a competitive environment with full enthusiasm and dedication. 
 It may be noted that candidature will remain provisional till the veracity of the concerned documents are verified by the Appointing Authority. 
 Qualification and experience in the relevant field alone will be considered 

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