POSITIONS AVAILABLE
12th October 2021
Applications are invited for the position of TWO Research Associate in the DST funded project entitled “National Centre for Screening of Natural Products for Parasitic diseases”.
Candidates must have qualified NET.
POSITION 1
The project will be focused on screening of small molecule inhibitors against the proteasomes of E. histolytica.
Essential qualification: PhD in any branch of Biological Sciences with at least one first author paper.
Desirable: The candidate must have extensive experience in protein purification techniques along with some basic knowledge of molecular/cell biology techniques and animal cell culture. Experience in molecular modelling and optimization of compound series via structure-based drug design is desirable. Candidates with prior work experience with Entamoeba histolytica, along with abovementioned qualifications will be given preference.
POSITION 2
Essential qualification: PhD in any branch of Biological Sciences with at least one first author paper.
Desirable: The candidate must have basic knowledge of molecular/cell biology techniques and animal cell culture. Candidate should be proficient in the following genetic engineering based recombinant DNA technologies:
- Bioinformatics including primer designing, phylogenetic analysis, comparative genomics and proteomics analysis, homology modelling and virtual docking.
- Molecular biological techniques including gene cloning; and, protein expression & purification.
- Functional complementation assays in gene-knockout strains of Saccharomyces cerevisiae.
- Genetic manipulation (genome editing) in the protozoan parasites: Leishmania donovani and Plasmodium falciparum. Includes synthesis of recombinant plasmid constructs for CRISPR/Cas9-mediated gene editing; and, miRNA and siRNA-mediated mRNA knockdown, followed by electroporation-based transfections in the parasites.
- Biophysical techniques including Surface Plasmon Resonance (SPR), Isothermal Titration Calorimetry (ITC), Fluorescence spectroscopy, Circular Dichroism (CD), Time Resolved Fluorescence Spectrometry (TRFS), Raman spectrometry and Capillary electrophoresis.
Candidates with prior work experience with Leishmania donovani and Plasmodium falciparum cultures, along with above mentioned expertise will be given preference.
Candidates should submit a brief (about 1 page) summary of their research work and a copy of their CV (with names and e. mail contacts of two referees) along with the application.
Salary: INR 47000/- p.m.
The position is co-terminus with the project
The applications should be addressed to Dr. Rohini Muthuswami and must reach by 17:30 pm on 29thOctober by email as follows:
For Position 1: Email: swatijnubt@gmail.com
For Position 2: Email: shailjasngh@gmail.com
The subject line of the Email should be in the format “your name_RA_applicant_DPRP”.
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