Post: Senior Research Fellowship
Duration: 3 years
ICMR Project: Elucidation of neurodegenerative tauopathies through MARK4 inhibitors: Design and
evaluation of MARK4 inhibitors using insilico and invitro approaches and investigation
of their role to cure hyper phosphorylation of tau proteins
Project Description: Interested candidates are welcome to apply for SRF for a comprehensive drug
discovery project aimed to discover potential kinase inhibitors. A strong connection exists between
phosphorylation and tau pathology has laid the foundation to hunt for tau kinase inhibitors as potential
therapeutics. We believe that the MARK4 is one of the most promising kinases that should be targeted
as it initiate tau phosphorylation cascade. In this project we aimed to identify potent kinase inhibitors.
The selected mixture of the extract will be further tested that how efficiently it could attenuate hyperphosphorylation of tau, and thus clears the tau mediated aggregates indifferent neuronal human cell
lines. Our integrated approach will be key in identifying novel kinase inhibitors for therapeutic
management of MARK4-related tauopathies, Alzheimer disease, and neuro-inflammation.
Essential Qualification for SRF 1 (Biological Science): Applicant with expertise in Molecular
Biology/Cell Biology/Structural Biology/Bioinformatics (especially MD simulation) and good
command in oral and written communication skills in English will be given preference.
Essential Qualification: M. Sc. in any stream of Biological Science with at least 55% marks and
Two Years of research experience. Preference will be given to NET/GATE qualifiers.
How to apply: Please submit a cover letter, attached application form, CV, and supporting documents
combined into a single PDF file and also fill the attached form and send by e-mail
to aislam@jmi.ac.in on or before May 20, 2022.
Principal Investigator
Dr. Asimul Islam
(Associate Professor)
Centre for Interdisciplinary Research in Basic Sciences
Jamia Millia Islamia, Jamia Nagar
New Delhi 110025, INDIA
E-mail: aislam@jmi.ac.in
General Instructions:
Incomplete forms will not be accepted.
Guidelines of funding agency to recruit manpower will be applicable.
Only shortlisted candidates will be communicated to appear for the interview.
Original certificates need to be presented before the interview for verification.
Interviews may be conducted through online mode.
Application for Senior Research Fellowship
Name:
Sex:
Father’s Name:
Date of Birth:
Address:
Mobile No.
E-mail:
Education:
Course Major subject Year University Grade/
Percentage
B.Sc.
M.Sc.
Others
NET/GATE Score:
Title of M.Sc. Dissertation:
Experience:
Name of
Organization
Designation From To Role
Description of Research Project(s) Handled:
Technical Expertise:
Date
Place Signature
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