Workshop on Cancer Proteogenomics
SEPTEMBER 26 - 30, 2016
Cancer research is rapidly evolving with advancements in high-throughput profiling technologies such as liquid chromatography-based tandem mass spectrometry (LC-MS/MS) and next generation sequencing(NGS) technologies. Cancer samples are increasingly subject to "proteogenomic" analysis whereby proteomic data from LC-MS/MS profiling and genomics data from NGS technologies are analyzed in an integrated manner. With copy number and sequence variations at the genome level, splice variants and RNA editing at the transcriptome level, and diversity of protein products and their post-translational modifications(PTMs), proteogenomics can help comprehend the link between the cancer genome and its clinical phenotype. Proteogenomic analysis of large-scale studies involves computational challenges not only in dealing with the sheer scale of the data, but also in meaningful integration of LC-MS/MS and NGS data to derive biological insight. The main purpose of this WORKSHOP ON CANCER PROTEOGENOMICS 2016 is to address many of these challenges.
To comprehend advances in proteogenomics and to bring together biologists and bioinformaticians to tackle challenges in the analysis profiling technologies, the Rajiv Gandhi Centre for Biotechnology and the Broad Institute of MIT and Harvard University are jointly organizing this residential workshop from 26th to 30th September 2016.
The five-day workshop will provide a strong foundation in proteogenomic analysis, integrating data from LC-MS/MS and NGS technologies. This workshop, presents an exciting agenda, with interactive lectures and case-studies, combined with hands-on sessions, to explore the challenges of cancer proteogenomics, and presents new innovative ways to tackle them. The first part of the workshop will cover the general principles of available genomics, proteomics, statistical data analysis and machine learning. The latter part of the workshop will apply these principles and algorithms to the analysis of breast cancer data. Hands-on exercises will accompany lectures throughout, and illustrate practical application to real-world data. The workshop will include discussions and open exchange of ideas to foster scientific collaboration and promote adoption of methods in participants' home institutions.
WHY ATTEND ?
WORKSHOP ON CANCER PROTEOGENOMICS 2016 will be a milestone event in the cancer community. This workshop will consist of:
- Lectures by experts from Broad Institute of MIT and Harvard University.
- Demonstrations of NGS and Proteomics data analysis software and other relevant cancer bioinformatics resources.
- Complete hands-on session on each day, consisting of data analysis exercises that will enable the participants to apply statistical and machine learning methods to the analysis of proteogenomic data, under the guidance of the lecturers and teaching assistants.
- Interactive lectures with discussions and case studies illustrating different ways of analyzing proteomics and NGS experiments to promote biological insight and understanding.
More Info : http://rgcb.res.in/ProteogenomicsWorkshop2016/