3rd INDIAN CANCER GENETICS CONFERENCE & WORKSHOP 2016
(An Indo-UK Program)
7-14 December, 2016
Advanced Centre for Treatment Research & Education in Cancer (ACTREC)
Tata Memorial Centre, Navi Mumbai, India
PROGRAMME HIGHLIGHTS
7–11 December 2016: Three Parallel Hands on Training Workshops
Faculty:
Prof. Rajiv Sarin (Chair and Co- Convenor)
Prof. Shirley Hodgson (SVH), St George’s Hospital Medical School, London , UK
Prof. Gareth Evans, (GE), Genetic Medicine, St Mary’s Hospital, Manchester, UK
Dr. Victoria Murday (VM) Consultant Clinical Geneticist, Glasgow, Scotland, UK
Prof. Meena Upadhyaya (MU) Cardiff University, UK
Dr. Margret Ausems (MA), Consultant Cancer Geneticist, University Medical Centre Utrecht, Utrecht, The Netherlands
Convenor Prof. Dhavendra Kumar, Institute of Medical Genetics, University Hospital of Wales, Cardiff University School of Medicine , UK
Chair Indo-UK Genetic Forum and Co-Convenor
• NGS (5 days 7-11th December): Sample preparation and QC on Qubit & Bioanalyser; Library preparation for whole Exome and Transcriptome sequencing on Illumina HiSeq; Bio-informatics analysis for exome and transcriptome
• Methods in Molecular Genetic Analysis (4 days 8-11th December): Troubleshooting PCR, Different applications of PCR including methylation specific PCR, Different Genotyping techniques (CSGE, RFLP, TaqMan assay), Haplotyping, Sanger Sequencing, RT-PCR, MSI analysis, MLPA, IHC, Immunofluorescence & Tissue Microarray
• Genetic counseling (4 days 8-11th December): Counselling methods, pedigree analysis, verbal autopsies, syndrome identification, mutation probability estimation, screening algorithms & clinical management of mutation carriers
12-14 December 2016: Cancer Genetics Conference
3 day Conference with 7 international faculty from the UK and The Netherlands and 8 Indian faculty, all experts in Clinical or Molecular Cancer Genetics
Lectures, Case Based Discussions, Round Table & Role Plays will cover general and specific aspects of diverse hereditary cancers, genetic susceptibility to cancer, molecular genetic analysis from Sanger Sequencing to NGS, Interpretation of Genetic Analysis results, screening, chemoprevention and surgical prophylaxis in carriers for different gene mutations.
Registration : https://tmc.gov.in/ICGCW/
More Info :
http://www.actrec.gov.in/data%20files/Meetings/2016/Combined%20programme%20ICGCW2016.pdf
Day 1: Monday, 12th December 2016
Introduction to Inherited Predisposition to Cancer & its Molecular Basis Counselling & Indian Scenario Chairpersons: Prof. Dhavendra Kumar & Prof Rajiv Sarin | ||
08.30-09.30 | Registration and tea |
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09:30 -09:40 | Welcome address |
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09:40 -10:05 | Cancer Genetics & Cancer Immunology: The meeting point | Prof. Shubha Chiplunkar, ACTREC,Mumbai,India |
10:05-10:30 | Cancer predisposing genes - Tumour Suppressor Genes, Oncogenes & beyond | Prof. Shirley Hodgson, London and Leicester, UK |
10:30 – 10:55 | Inherited Predisposition to Cancer: The Indian Perspective | Prof. Rajiv Sarin,TMC Mumbai, India |
10:55-11:20 | Molecular Genetic analysis: Past, present and future | Dr Arindam Maitra, NIBMG, Kolkata,India |
11:20–11:45 | Tumour Mutations and Precision Oncology | Prof. Kumar Prabhash, TMH, Mumbai,India |
11:45 – 13:00 | Lunch & Poster Viewing |
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Breast, Ovary & Prostate Cancer: Genetics & Risk management (screening, surgery & chemoprevention) Chairpersons: | ||
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13:00 - 13:25 | Inherited Predisposition to Breast Cancer: Genetic basis; clinical manifestations; Penetrance of BRCA1/2 & other genes | Prof. Gareth Evans, Manchester, UK |
13:25 - 13:50 | Inherited Predisposition to Breast Cancer: Surveillance & Prophylactic Bilateral or Contralateral Mastectomy | Dr. Margreet Ausems, Utrecht, Netherlands |
13:50 - 14:10 | Inherited Predisposition to Breast Cancer: Chemoprevention | Dr Shona Nag,Jehangir Hospital, Pune, India |
14:10 - 14:35 | Inherited Predisposition to Ovarian Cancer: Genetic basis & clinical manifestations including penetrance, Surveillance & Risk Reducing Salpingo-Oopherectomy | Prof. Gareth Evans, Manchester, UK |
14:35 - 15:00 | Inherited Predisposition to Prostate Cancer: Genetic Testing and Risk Management | Dr. Margreet Ausems, Utrecht, Netherlands |
15:00 – 15:30 | Tea Break & Street Play – Genes running amock |
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Clinical and Laboratory Cancer Genetics Services in India Chairperson: Prof. Lalit Kumar: | ||
15:30 - 16:30 | Genetic Testing for Cancer in India: Industry perspective | 4 Private Labs (TBA) |
16:30 – 17:30 | Cancer Genetics Services – Report from Indian Hospitals | _ institutions (TBA) |
17:30- 18:10 | Establishing Cancer Genetic Services – affordable, actionable and timely testing, risk management of mutation carriers, VUS, Ethical Legal & Social issues UK faculty (2); Prof. T Rajkumar, Adyar, Prof. Lalit Kumar, Dr Sudeep Gupta, Dr Amita Maheshwari, Dr Vani Parmar, (Moderator: Rajiv Sarin) | |
18:15 - 18:45 | General Body Meeting of the Indian Society for Cancer Genetics | |
19:00 – 22:00 | Entertainment, Mela & Dinner in ACTREC Lawns |
Day 2
Tuesday, 13th December 2016
DNA Repair mechanisms; Hereditary Colorectal Caners; Li-Fraumeni syndrome & XP Chairpersons | ||
09:30 -09:55 | DNA repair mechanisms & cancer: A mechanistic insight | Dr Sorab Dalal, ACTREC,Mumbai,India |
09:55 – 10:20 | Germline Genetic Alterations and choice of systemic therapy | Prof. T Rajkumar, Chennai,India |
10:20 - 10:45 | Hereditary Non-Polyposis Colon Cancer (Lynch) Syndrome: Genetic Analysis and Surveillance | Prof. Shirley Hodgson, St. Georges, London, and Leicester, UK |
10:45 -11:10 | Colorectal Cancers: A biologist’s perspective | Dr Murali Bhashyam,CDFD Hyderabad, India |
11:10 – 11:30 | Tea break |
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11:30 – 11:50 | Polyposis Syndromes | Prof. R. Sarin, TMC,Mumbai,India |
11:50 – 12:10 | Prophylactic & Therapeutic surgery in FAP & Lynch Syndrome | Dr Avinish Saklani, TMC,Mumbai,India |
12:10 – 12:40 | Li Fraumeni syndrome & TP53 | Prof. Gareth Evans, Manchester, UK |
12:40 – 13:00 | XP | Dr Pradnya Kowtal, ACTREC,Mumbai,India |
13:00 – 14:00 | Lunch & Poster Viewing |
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Rare Cancer Predisposition Syndromes Chairpersons: | ||
14:00 - 14:25 | MEN syndromes | Dr. Victoria Murday, UK |
14:25 - 14:50 | Paraganglioma & other are endocrine tumours | |
14:50- 15:15 | Cowden (PTEN) | Prof. Shirley Hodgson, UK |
15:15 - 15:40 | Tuberous Sclerosis & Gorlin Syndrome | Prof. Gareth Evans,UK |
15:40 - 16:05 | VHL & inherited renal cancers | Dr. Victoria Murday,UK |
16:05 – 16:25 | Tea break |
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16:25 -17:30 | SS Agarwal Oration: (Chairpersons: Prof. S. Chiplunkar / Dr MG Deo | |
| “Our Footprints on the Sands of Time” | Prof. Partha Majumder,NIBMG Kolkata,India |
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19:00 – 22:00 Hrs Dinner |
Day 3
Wednesday, 14th December 2016
Inherited Childhood Cancer Predisposition
Chairperson: | ||
09:30 - 09:50 | Histopathological features indicating underlying genetic alterations | Dr Poonam Gera, ACTREC, Mumbai |
09:50 - 10:10
| Clinical Genetic Approach to Pediatric Tumours | Prof. Dhavendra Kumar, Cardiff, UK |
10:10 – 10:30 | Retinoblastoma | Dr Girish Chinnaswamy, TMH, Mumbai India |
10:10 – 10:30 | RAS / MAP Kinase Pathway Syndromes | Prof. Meena Upadhyaya, Cardiff, UK |
10:30 – 10:50 | NF1 and NF2 | Prof. Gareth Evans, UK |
10:50 - 11:10 | Tea Break |
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11:10 - 11:30 | Prenatal and Preconception genetic diagnosis | Dr Parag Tamhankar, NIRRH, Mumbai |
11:30-12:10 | Role play followed by case based discussion on issues in genetic testing including prenatal testing, clinical management and cancer prevention in children | Tushar Vora, Tejpal Gupta, Banavali, dr Agarwal (Genepath), UK |
12:10:12:30 | Pharmacogenomics in modern medicine | Dr Vikram Gota, ACTREC, Mumbai |
12:30-12:50 | The Global BRCA Challenge | Prof. Dhavendra Kumar |
12:50-13:40 | LUNCH |
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13:40-14:40 | Debate for and against “Personalized Genomic - Hope or Hype” |
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14:40 – 15:30 | Oral presentations | 5 presentations |
15:30 – 16:30 | Best Paper Session | 6 presentations |
16:30 – 17:00 | Participant Feedback, awards & closing Remarks |
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