VACANCY NOTICE
POSITIONS AVAILABLE AT BIOFOUNDRY, ICGEB, NEW DELHI
Department of Biotechnology (DBT), Govt of India, has funded a Biofoundry project at
ICGEB to perform AI-ML-guided strain engineering of yeast and E. coli. The following
positions are available for the project initially for one year, which may be extended further
based on the performance and the project's tenure. These are temporary project positions
whose durations are only up to the tenure of the DBT-funded project.
1. Project Scientist II -(5 positions)
(i) Position area – Computational Biology (PI – Dr. Dinesh Gupta)
Job description:
• Develop and implement computational pipelines for high-throughput omics data (e.g.,
genomics, transcriptomics, metabolomics)
• Build and optimize machine learning models to guide strain design and pathway
optimization
• Integrate multi-modal datasets into cohesive systems biology models
• Collaborate with wet-lab scientists to close the DBTL loop and improve biofoundry
workflows
• Contribute to software tool/database development, and presentations
Qualifications:
• Essential:
o PhD in Bioinformatics/Computational Biology/ Systems Biology, Computer
Science, or related field. Strong programming skills (Python, R, or equivalent)
o Experience with multi-omics analysis, metabolic modelling
o Experience of using or developing ML/AI techniques
o Experience of Structural Bioinformatics, molecular modelling and running MD
simulations
o Familiarity with synthetic biology concepts and genome engineering
o Excellent communication and collaboration skills
o Publications in the above mentioned experience areas
• Desirable:
o Experience of working in a biofoundry project or synthetic protein design,
bioprocess optimization.
o Experience of working in a HPC environment
(ii) Position area – Systems Biology (PI – Dr. Shireesh Srivastava)
Job description: The position involves computational design and analysis of metabolic
pathways in E. coli and yeast using methods of metabolic systems biology such as Flux
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Balance Analysis, Computational Biology tools, and Integration of Omics data. The
candidate will also be responsible for timely conduct of analyses and preparation of
reports, maintenance of computers, software and databases related to the project, and
participation in training activities conducted by the group.
Qualifications: Ph.D. in Biotechnology, Computational Biology, Chemical Engineering
or related fields. Candidate must be well versed in Windows and Linux-based operating
systems and have prior experience in computational analyses. Candidates with prior
knowledge of MATLAB, Metabolic modelling and analysis, Metabolic databases,
COBRA toolbox, Omics data analysis will be preferred.
(iii) Position area - Functional genomics (PI – Dr. Pavan Jutur)
Job description: This position involves a motivated functional genomics expert to design
and execute experiments unraveling gene function within our biofoundry. The role heavily
involves integrating and analysing multi-omics data to optimise strain engineering,
collaborating with biologists and data scientists for accelerated R&D.
Qualifications: Ph.D. in Biotechnology, Life Sciences, or a related field with at least 3
years of experience is required. Mandatory experience handling microbial strains, with
knowledge in omics biology.
(iv) Position area – Yeast engineering (PI -Dr. Naseem Gaur)
Job description: The candidate will be responsible for developing genetically engineered
yeast strains as per the project requirements. This will involve synthetic biology and
metabolic engineering approaches to build the customised engineered yeast strains as a
chassis for biomanufacturing.
Qualifications: Ph.D. in Biotechnology or related field with 3 years of experience.
Candidates with a strong molecular biology background, analytical skills, and critical
thinking ability will be preferred.
(v) Position area – E. coli engineering (PI – Dr. Shams Yazdani)
Job description: The work will involve engineering the genome of E. coli for producing
various fuels and chemicals. The metabolic pathway design, synthesis, assembly and
integration in the genome with the help of various genetic/genome engineering tools will
be the major part of the project. Protein engineering, wherever needed, will also be
involved in the project.
Qualifications: Ph.D. in Biotechnology or related field with 3 years of experience. The
candidate with strong molecular biology, synthetic biology, genome engineering, and
metabolic engineering will be preferred.
Salary – Rs 67,000 per month + HRA
2. Project Associate II (2 positions)
(i) Position area – Yeast Engineering (PI – Dr. Naseem Gaur)
Job description: The candidate will be responsible for executing molecular biology and
biochemical experiments related to the development of genetically engineered yeast
strains and the bioprocess development of engineered yeast strains for product formation.
Qualifications: M.Sc./M.Tech in Biotechnology or a related field with 2 years of
experience
(ii) Position area – E. coli Engineering (PI – Dr. Shams Yazdani)
Job description: Design and construction of pathway genes in E. coli
Qualifications: M.Sc./M.Tech in Biotechnology or related field with 2 years of
experience
Salary – Rs 35,000 per month + HRA
3. Project Associate I (2 positions)
(i) Position area – Yeast Engineering (PI - Dr. Naseem Gaur)
Job description: The candidate will be responsible for executing molecular biology and
biochemical experiments related to the development of genetically engineered yeast
strains and the bioprocess development of engineered yeast strains for product formation.
Qualifications: M.Sc./M.Tech in Biotechnology or a related field
(ii) Position area – E. coli Engineering (PI - Dr. Shams Yazdani)
Job description: Construction and testing the engineered E. coli for product formation via
various analytical techniques.
Qualifications: M.Sc./M.Tech in Biotechnology or related field
Salary – Rs 31,000 per month + HRA
4. Project Manager (1 position) (PI – Dr. Ramesh Sonti)
Job description: Managing the Biofoundry project
Qualifications: PhD in Science or ME/MTech with 5 years of experience
Salary – Rs 1,25,000 per month (Consolidated)
5. Administrative Assistant (1 position) (PI – Dr. Ramesh Sonti)
Job description: Administrative support to the Biofoundry project
Qualifications: BSc or BA in any discipline
Salary – Rs 18,000 per month + HRA
6. Technical Manager (2 positions)
(i) Position area – Yeast Engineering (Dr. Naseem Gaur)
Job description: Technical support to Scientific staff members
Qualifications: BSc or 3yr Diploma in Engineering & Technology
(ii) Position area – E. coli engineering (Dr. Shams Yazdani)
Job description: Maintaining analytical equipments
Qualifications: BSc or 3yr Diploma in Engineering & Technology
Salary – Rs 20,000 per month + HRA
7. Lab Assistant (1 position) (PI – Dr. Ramesh Sonti)
Job description: Lab inventory maintenance, glassware/plasticware cleaning, etc
Qualifications: BSc in any field
Salary – Rs 20,000 per month + HRA
Interested candidates should email their latest curriculum vitae and cover letter (Cover letter
must mention pertinent skills) with a detailed description of relevant experience to
icgeb.biofoundry@gmail.com with Subject “Application for <(name
of the PI)> Position”. Only short-listed candidates will be contacted for an interview.
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