BRIC-THSTI Recruits Project Manager/Clinical Research Associate/Data Manager

RECRUITMENT NOTICE NO.: THS-C/RN/13/2025 Dated: 14th August 2025 

RECRUITMENT NOTIFICATION 

1. BRIC-Translational Health Science and Technology Institute (THSTI), BRIC-Translational Health Science and Technology Institute (THSTI) is an Institute of the Biotechnology Research and Innovation Council, Department of Biotechnology, Ministry of Science & Technology, Govt. of India. The institute is an integral part of the interdisciplinary NCR Biotech Science Cluster located at Faridabad, with the mission to conduct innovative translational research and to develop research collaborations across disciplines and professions to translate concepts into products to improve human health. 

2. BRIC-THSTI has built several inter-institutional collaborations and connectivity with industry supported by well-trained teams of research and laboratory staff. THSTI has established various centres namely (a) Centre for Maternal and Child Health, (b) Centre for Virus Research, Therapeutics and Vaccines (c) Centre for Tuberculosis Research (d) Centre for Microbial Research, (e) Centre for Immunobiology and Immunotherapy (f) Centre for Drug Discovery (g) Clinical Development Services Agency (h) Computational and Mathematical Biology Centre (i) Centre for Bio-design and Diagnostics. These centres are strengthened by many core facilities viz. Bioassay Laboratory, Biorepository, Biosafety Level-3 Lab, Data Management Centre, Immunology Core laboratory, Multi-Omics facility, Experimental Animal Facility, Vaccine design and Development facility, School of Innovation in Bio design etc. that serve as huge resources for the research programmes of THSTI and also the National Capital Region Biotech Science Cluster and other academic and industrial partners. BRIC-THSTI trains the next generation of scientific leaders through many ambitious and globally competitive academic courses which promotes research and innovation through multi-disciplinary academia-industry partnerships 

3. This recruitment is to fill up the vacancies of BRIC-THSTI under the following projects:

Educational Qualification and Experience required for the post: 

1. Name of the post Project Manager 

Name of the Project Effect of Immediate Kangaroo Mother Care (iKMC) on neonatal mortality and culture-positive sepsis in low-birth-weight neonates in district hospitals in Chhattisgarh, India: a stepped-wedge cluster randomized trial 

Emoluments INR 90,000 per month 

Age Up to 45 years

Location Based at AIIMS Raipur and travel to 10 District Hospitals in Chhattisgarh 

Minimum Educational Qualification and Experience Essential qualifications and work experience: 

• MBBS/BDS/BVSc with a minimum of five (5) years of experience in clinical project management and/or clinical trial/ study monitoring. OR 
• Master’s Degree / PG Diploma in Life Sciences / Biomedical Sciences / Pharmacy / Public Health / Clinical Research with at least five (5) years of experience in clinical project management and/or clinical trial/ study monitoring. AND 
• Experience in clinical trial or public health project management in a recognised organisation/institute (academic clinical trials unit, CRO, pharmaceutical, biotechnology, or medical device company) Desirable qualifications and work experience: 
• Postgraduate degree in Public Health 
• MD/DNB from a recognised Indian University/recognised by MCI 
• PhD in a health-related discipline • Demonstrable experience of line management, project management concepts, and ability to understand, explain and communicate 
• Project concepts using standard tools and templates.

Job profile 

• The Project Manager is responsible for overseeing, managing, and executing the operational aspects of assigned clinical studies and trials, ensuring the timely delivery of milestones while upholding the highest standards of quality, compliance, and scientific integrity. The role demands cross-functional leadership, operational excellence, and a strategic mindset to support complex clinical research programs Key Responsibilities: 
• Oversee and manage the performance of the project team, ensuring effective collaboration and accountability across functions. 
• Maintain the integrity of clinical trials by monitoring data, processes, and documentation through both onsite visits and remote oversight. 
• Conduct site qualification, initiation, monitoring, and close-out visits for assigned clinical trials/research studies. Must be willing to travel to clinical sites across India on short notice and stay for extended durations as needed. 
• Lead cross-functional coordination efforts, working closely to develop, implement, and maintain comprehensive project plans and timelines. Clearly communicate project expectations to all relevant team members and consultants. 
• Manage overall project budgets to ensure alignment with scope and financial objectives. 
• Support the implementation and maintenance of systems related to resource planning, study administration, monitoring, quality assurance, and documentation, under the supervision of the Chief - Clinical Portfolio Management (CPM). 
• Undertake additional responsibilities within the Clinical Portfolio Management team as required by project deliverables or organisational needs. 
• Establish and enforce procedures to ensure adherence to study protocols, regulatory requirements, and organizational standards. 
• Ensure adherence to applicable regulatory and ethical frameworks, including oversight by regulatory authorities, ethics committees, and other governing bodies. 
• Coordinate and support audit readiness and audit processes, including the development of Corrective and Preventive Actions (CAPAs). 
• Liaise with the Steering Committee and Data Safety Monitoring Board (DSMB) to ensure compliance with Research Governance, Good Clinical Practice (GCP), Data Protection, and Ethical Guidelines. 
• Prepare or oversee regulatory and ethics submissions, amendments, and responses to regulatory queries, ensuring timely approvals and renewals. 
• Develop and deliver project-specific and protocol-specific training, as well as additional training as requested. 
• Provide ongoing guidance, mentorship, and operational training to project staff as needed. 
• Serve as trainer for training initiatives conducted by CDSA. 
• Collaborate with Investigators to monitor study progress, ensure meaningful outputs, and support necessary protocol or funding amendments based on study findings or operational needs. 
• Facilitate partnerships with sponsors, collaborators, and regulatory bodies to support compliance, reporting, and trial visibility. 
• Engage external stakeholders such as funding bodies and governmental agencies to enhance trial impact and reach. 
• Oversee the development, approval, and distribution of essential study documents, including study protocols, Case Report Forms (CRFs), study manuals, and tools for investigational sites and review boards. 
• Manage regulatory documentation workflows, including distribution, collection, and tracking, ensuring compliance and audit readiness. 
• Collaborate with data management and other departments to monitor project milestones, assess challenges, and drive progress. 
• Evaluate, implement, and oversee clinical trial management systems (CTMS), electronic data capture (EDC), and eTMF systems. 
• Act as the point of contact for clinical systems integration, troubleshooting, and training. 
• Select, contract, and manage vendors and CROs, including central labs, data management providers, and technology partners. 
• Monitor vendor performance, adherence to timelines, and deliverables in accordance with study plans and quality standards. 
• Develop and maintain a study-specific Risk Management Plan. 
• Identify, monitor, and mitigate project risks, including protocol deviations, site issues, or compliance concerns. 
• Support protocol development, study design discussions, and ensure alignment with scientific and operational goals. 
• Assist in the development of manuscripts, conference abstracts, and publications derived from trial data. 
• Collaborate with site teams to implement patient recruitment, engagement, and retention strategies. 
• Promote inclusive research practices that support diverse participant enrollment and reduce barriers to access. 
• Track and reconcile project expenditures; oversee financial reporting and milestone payments. 
• Contribute to grant writing, funding proposals, and reporting to funding agencies or donors as needed. • Develop and analyse real-time performance dashboards to track site metrics, data quality indicators, issue resolution trends, and project milestones. 
• Frequently travel to assigned trial/study sites by eligible modes of travel, including city and state public transportation, own transportation, train travel, or private mass transport services, including standard and luxury buses. 

Skills 
• Demonstrated ability to build, lead, and mentor high-performing project teams. Skilled in motivating and inspiring others, effectively delegating responsibilities, and making timely, high-quality decisions in complex clinical settings. 
• Recognized for earning the trust and confidence of diverse stakeholders. Possesses a quick learning aptitude, managerial courage, emotional resilience, and a proactive mindset, particularly in dynamic and fast-paced environments. 
• Deep knowledge of Indian clinical trial regulations and a comprehensive understanding of global standards, including ICH-GCP and CDSCO guidelines. Committed to upholding the highest standards of regulatory and ethical compliance. 
• Strong grasp of clinical operations, project budgeting, and resource management. Demonstrates a continuous improvement mindset, with a focus on quality assurance, operational efficiency, and pragmatic problemsolving. 
• Exceptional ability to negotiate, influence, and align cross-functional teams and external partners. Approaches challenges with a collaborative, solution-oriented mindset that fosters consensus and drives results. 

2. Name of the post Senior Clinical Research Associate 

Number of the post Three (03)

Name of the Project Effect of Immediate Kangaroo Mother Care (iKMC) on neonatal mortality and culture-positive sepsis in low-birth-weight neonates in district hospitals in Chhattisgarh, India: a stepped-wedge cluster randomized trial 

Emoluments INR 75,000 per month 

Location Based at AIIMS Raipur and travel to 10 District Hospitals in Chhattisgarh 

Minimum Educational Qualification and Experience 

• Bachelor's in Life Sciences with a minimum of three years of relevant clinical trial monitoring or clinical trial/study coordinator, or clinical trial/study associate experience. OR 
• Master’s degree/ diploma, life sciences, pharmacy, public health, healthcare or other related discipline with a minimum of 2 years of relevant clinical trial monitoring or clinical trial/study coordinator, or clinical trial/study associate experience. OR 
• MBBS/ BDS/ BHMS/ BAMS/ BPT with a minimum of 2 years of relevant clinical trial monitoring or clinical trial/study coordinator, or clinical trial/study associate experience.

Job profile 

• The Sr. Clinical Research Associate (CRA) is responsible for overseeing clinical trial sites from initiation to closeout, ensuring compliance with study protocols, ICH-GCP, applicable regulations, and internal SOPs. 

Responsibilities include: 
• Conduct monitoring visits (on-site and remote), including initiation, routine monitoring, and closeout. 
• Ensure trial sites comply with regulatory, protocol, and GCP requirements. 
• Conduct risk-based monitoring and escalate site issues and protocol deviations appropriately. 
• Verify informed consent and subject safety in alignment with ethical standards. 
• Monitor AE/SAE reporting timelines to ensure compliance with regulatory requirements and escalate delayed submissions to the pharmacovigilance team. 
• Review source documents and CRFs to verify data accuracy and consistency (SDV). 
• Ensure appropriate management and documentation of investigational product (IP). 
• Maintain essential trial documents in accordance with ICH GCP and local regulations. 
• Prepare detailed monitoring visit reports and manage action items. 
• Support regulatory and ethics submissions, patient recruitment, and resolution of data queries. 
• Provide training to site personnel on study protocols, GCP, and SOPs. 
• Ensure timely delivery and proper handling of study supplies and investigational product. 
• Monitor quality metrics and assist with CAPA implementation. 
• Ensure site readiness for audits and regulatory inspections. 
• Use clinical trial systems (EDC, CTMS, eTMF) for tracking, documentation, and communication. 
• Collaborate cross-functionally with clinical operations, data management, safety, and regulatory teams. • Maintain effective communication with investigators and site staff to ensure study success. 
• Frequently travel to assigned trial/study sites by eligible modes of travel, including city and state public transportation, own transportation, train travel, or private mass transport services, including standard and luxury buses. 

Skills 
• Proficient in computer applications, with demonstrated expertise in Microsoft Office Suite (Word, Excel, PowerPoint, Outlook). 
• Strong knowledge of ICH-GCP, GCLP, and regulatory guidelines. 
• Excellent documentation, communication, and organizational skills. 
• Detail-oriented with effective time management skills and ability to manage multiple tasks and priorities efficiently. 

3. Name of the post Assistant Data Manager (Level II)

Name of the Project Effect of Immediate Kangaroo Mother Care (iKMC) on neonatal mortality and culture-positive sepsis in low-birth-weight neonates in district hospitals in Chhattisgarh, India: a stepped-wedge cluster randomized trial 

Emoluments INR 90,000 per month 

Age 45 years 

Location THSTI 

Minimum Educational Qualification and Experience 

Essential qualification and work experience: 

• Master’s degree in any field preferably in science, with 6 years of postqualification experience in clinical data management/clinical research/operations/MIS/data analysis/IT/computer science/healthcare field OR 
• Graduation degree in any field preferably in science, with 8 years of postqualification experience in clinical data management/clinical research/operations/MIS/data analysis/IT/computer science/healthcare field 

Desirable qualification and work experience: Diploma in Information Technology/ Computer Applications/ Clinical Data Management. Familiarity with industry standard CDMS and some programming skills. Demonstrated experience of developing Clinical Study Data Management documents  

Job profile 

• Overall responsible for taking lead of all the data management activities for the mentioned study, timely delivery of key tasks, while maintaining high quality standards. 
• Escalate concerns related to variables that are critical to study quality and outcomes. 
• Develop and implement automation solutions to reduce manual errors and improve process efficiency. 
• Generate routine and ad-hoc reports to track study progress, identify potential issues, and flag non-compliance trends. 
• Serve as the primary point of contact for all data-related communications with the sponsor and clinical sites. 
• Collaborate with cross-functional project teams to support the planning, execution, and closure of study-specific data management tasks. 
• Conduct database testing and audits as part of internal quality control measures. 
• Prepare and review essential data management documentation, including the Data Management Plan (DMP), Data Validation Plan (DVP), Annotated CRF, and Data Entry Guidelines. 
• Manage query resolution, data cleaning, interim/final data freezes, and data archiving activities. 
• Process and transform raw data to ensure accuracy, completeness, and consistency. 
• Lead the development of clean, analysis-ready datasets in compliance with data protection and regulatory standards. 
• Generate interim study reports and support data extraction in coordination with the sponsor and coordinating centers. 
• Apply logical reasoning and robust data management techniques to ensure data integrity and validity. 
• Utilize data visualization tools (e.g., Tableau, Power BI, advanced Excel) to design interactive dashboards and generate visual insights based on project needs to support decision-making and reporting. 
• Coordinate the secure archiving of study databases and associated documentation. 
• Develop, implement, and maintain Standard Operating Procedures (SOPs) and work instructions; provide training to study staff as required. 
• Demonstrate hands-on experience in both paper-based and electronic CRF (eCRF) development and maintenance. 
• Represent the data management function in internal cross-functional meetings and external client discussions. 
• Ensure strict adherence to data security protocols and participant confidentiality throughout the study. 
• Apply working knowledge of CDM best practices, database development standards, and industry frameworks including CDISC and SDTM. Supervise site-level data management activities to ensure adherence to protocol and study timelines. 

Skills 

• Good management & leadership skills. 
• IT literate (experience with Microsoft based applications, data visualization tools and other data management applications). 
• Must have experience in handling databases and query management. 
• Client focused approach to work 
• Meticulous attention to detail. 
• Must be able to work independently but seek guidance when necessary. 
• Team player with outstanding inter-personal, negotiation skills and organizational skills. 
• A flexible attitude with respect to work assignments and new learning. 
• Effective time management in order to meet metrics or team objectives. 
• Commitment to project and team goals. 
• Demonstrated ability to solve complex tasks and complete work on time 
• Commitment to deliver high-quality work consistently Ability to model behavior and ethics in line with CDSA Mission and Vision 

4. Name of the post -Assistant Data Manager (Level I)

Name of the Project Effect of Immediate Kangaroo Mother Care (iKMC) on neonatal mortality and culture-positive sepsis in low-birth-weight neonates in district hospitals in Chhattisgarh, India: a stepped-wedge cluster randomized trial 

Emoluments INR 60,000 per month 

Location THSTI 

Minimum Essential: 

• Master’s degree in any field preferably in science, with 4 years of postqualification experience in clinical data management/clinical 

Educational Qualification and Experience research/operations/MIS/data analysis/IT/computer science/healthcare field OR 
• Graduation degree in any field preferably in science, with 6 years of postqualification experience in clinical data management/clinical research/operations/MIS/data analysis/IT/computer science/healthcare field 

Desirable: Diploma in Information Technology/ Computer Applications 

Job profile Responsibilities: 

• Assist in drafting, updating, and maintaining data management documents including the Data Management Plan (DMP), Edit Checks Document, Annotated CRF, Data Entry Guidelines, and SOPs. 
• Contribute to the design and development of paper Case Report Forms and electronic Case Report Forms (CRFs). 
• Collaborate with the Data Science team in database development, edit check implementation, and database testing. 
• Enter and manage test data to support screen and database validation processes. 
• Support data cleaning activities including query management, interim and final data freezes, and data archival. 
• Collaborate with other project team members to support the set-up, maintenance, and closure of data management activities. 
• Assist in preparing interim reports, performing data extraction, and supporting ongoing data review. 
• Apply working knowledge of data standards (e.g., CDISC, SDTM), clinical data management practices, and SOPs. 
• Provide training to site-based data entry operators, if required. 
• Support data entry and data reconciliation activities as assigned. 
• Assist in preparing analysis-ready datasets and ensuring compliance with data protection and privacy standards. 
• Contribute to the creation of reports and dashboards to monitor study performance. Provide general support to the Data Science team for any additional studyrelated tasks. 

Skills 

• Familiarity with GCP, 21 CFR 11, regulatory requirements and data standardization guidelines. 
• IT literate (experience with Microsoft based applications and other CDMS applications). 
• Must understand clinical research and familiarity with clinical data management functions. 
• Good interpersonal, verbal and written communication skills. 
• A flexible attitude with respect to work assignments and new learning. 
• Effective time management in order to comply to timelines. 
• Commitment to project and team goals. 
• Must be able to work independently but seek guidance when necessary. 
• Demonstrated ability to solve complex tasks and complete work on time 
• Must be a team player 
• Ability to model behavior and ethics in line with CDSA Mission and Vision 

For posts mentioned above- 

➢ Last date for receipt of online application for posts: 03 September 2025. 
➢ The applications will be scrutinised/shortlisted and processed for further selection. 

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