NATIONAL INSTITUTE OF BIOMEDICAL GENOMICS
P.O.: N.S.S., Kalyani 741251, West Bengal
National Supercomputing Mission (NSM) Platform for Genomics and Drug Discovery:
Development of a fast, flexible, high performance computing framework to accelerate NGS
omics-data analysis
Massively Parallel Sequencing or Next Generation Sequencing (NGS) has taken the scientific
community by storm. After commercial availability of the technology from last decade
onwards, even modest sized laboratories and institutions all over the world can effectively
produce petabytes of data in weeks. Earlier the most robust Sanger sequencing technology
can only generate 0.003 Gb of sequence data in a month whereas the present day an average
next generation sequencers can generate 50000 Gb per month. This revolution in data
generation technology, warrants an array of statistical and computational advancement to
translate information into knowledge. The stumbling blocks in translating the large volume
of data (information) to biologically relevant inferences (knowledge) range from (a)
information storage, retrieval of the raw data as-is generated from the sequencing machine -
(b) large-scale fast computation and processing that is essential for the data to be useable by
the general scientific community – (c) sophisticated analysis that is required in transforming
the enormous information to knowledge. Of the above, currently, (a) and (b) almost entirely
falls in the domain of computational experts and basic scientists without appropriate
competence in computational skills, fail to engage. Moreover, a full appreciation of (a), (b)
and (c), particularly (b) and (c), require access to highly powerful computer architecture;
which is even beyond the capability of a modest institute, let alone an individual.
The objective of this project is to make available an easy and extremely flexible
supercomputing analysis framework, preferably web-based, to the basic scientist. This would
enable them to exercise their choice of programs sequentially in a seamless fashion to process
the raw sequence data in accordance to their need and choice (i.e. (b)). It will also provide the
research a wide array of tools for sophisticated data-analysis (i.e. (c)). The project also would
keep in record, the usage of the programs and would analyze the data to optimize and
synchronize among different programs and modules.
We are looking for motivated and bright individuals interested to explore career opportunities
in this innovative multi-organization initiative in National Supercomputing Mission (NSM) at
NIBMG in the positions mentioned as below:
NSM Bioinformatics
Engineer
Tier - I
2 25000/-
MSc/M.Tech/B.Tech in
Bioinformatics/Bioengineering/Biophysics
Experience in webdevelopment skills
(html, CSS, PHP, JS);
Knowledge in
UNIX
(1) Experience in
R or Python
(2) Experience in
database
development
skills
(html,CSS,PHP,J
S)
(1)
Bioinformatics
pipeline
building and
testing.
(2) Data
analysis
(3) Report
writing
These positions are contractual and appointments will be initially given for one year, which are
extendable depending upon performance and requirements of the project.
Please apply online at https://apply.nibmg.ac.in (no other form of application will be accepted).
The
last date of application is 29th September 2020 (Tuesday upto 5PM).
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