INDIAN INSTITUTE OF TECHNOLOGY BOMBAY
POWAI,
MUMBAI 400076
Job Title
Research Associate
Job Reference Number
50206605
Application End Date
12.04.2021
Project title: Investigation of function of kinetochore on 3D organisation and condensation of
chromosomes during mitosis and meiosis using budding yeast as a model system
About the project: Faithful chromosome segregation is very crucial for resisting generation of
aneuploidy which is responsible for several disease states. The kinetochore complex is a megadalton
complex that connects the chromosomes with that of the microtubule spindle, and plays the key role
in chromosome segregation. Besides attaching the chromosomes with the spindle, the kinetochore is
believed to act as a hub to cater several other functions pertaining to the chromosome segregation.
In this project, we would investigate the function of kinetochore on condensation of the chromosomes
and how through this function it can modulate the positioning of the chromosomes in 3D space of the
nucleus. We would examine if there is any variation of these functions between mitotic and meiotic
cell divisions. For this work, we will use budding yeast Saccharomyces cerevisiae, a popular
eukaryotic model for studying the cell cycle.
Essential Qualifications & Experience:
Ph.D/MD/MS/MDS or equivalent degree or having 3 years of research, teaching and design and
developement experience after MVSc/M.Pharm/ME/M.Tech with at least one research paper in
Science Citation Indexed (SCI) journal
More than 75% marks in Masters degree and more than 65% marks in bachelor degree will be
preferred.
Six months to one year experience of work on Next Generation Sequencing including
ChIP-Seq, Hi-C, RNA-Seq (wet lab experiment and bioinformatics of data analysis) will be highly
preferred. Experience in working on yeast (S. cerevisiae) will also be preferred
Job Profile:
Wet lab experiments of Mol Bio, Cell Bio and Biochemistry with sample and library preparation
related to NGS. Data maintenance, Bioinformatics analysis of NGS data and scientific report writing.
Pay Details:
Consolidated salary Rs.47000/- p.m. + HRA
General information:
The position is temporary for a period of 1 year and tenable only for the duration of the project.
The appointment is for time bound project and the candidate is required to work mainly for the
successful completion of the project. The selection committee may offer lower or higher designation
and lower or higher salary depending upon the experience and performance of the candidate in the
interview.
Candidates called for interview will be required to attend at his/ her own expenses.
For any queries/clarification please contact: recruit@ircc.iitb.ac.in
More Info:
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