Advertisement No. NIBMG/ADMIN/ESTB/2025-26/47 Date: 22-05-2025
Project name: Evaluation of spatial ecology of Tie2-activated myofibroblastic-CAFs as potential target
against aggressive oral cancer
Funding Agency: DBT
Project tenure: 3 years
Principal Investigator’s name: Prof. Sandeep Singh
Project Description: This project is focused on evaluating the cellular composition and its spatial
arrangements with respect to the Tie2-activated myofibroblastic-CAFs at a single-cell resolution in oral
tumors. Multi-dimensional analysis will be performed to identify spatial compositions that can
eventually correlate with patient prognosis. Also, we will test novel designs of the small molecule
inhibitors against activated Tie2 and evaluate its impact on cancer evolution driven by activated Tie2 in
oral TME using cell culture models and mouse models of oral cancer.
PA-I 1
(i) INR 31,000 + 24%
HRA to be given who
are selected through
(a) National Eligibility
Tests – CSIR-UGC NET
including lectureship
(Assistant
Professorship) or GATE
or
(b) A selection
process through
National level
examinations
conducted by Central
Government
Departments and their
Agencies and
Institutions.
(ii) INR 25,000 + 24%
HRA for others who do
not fall under (i) above.
Essential Qualifications Post
Graduate
Degree in
Natural Sciences
or bachelor’s
degree in
engineering or
technology or
medicine from a
recognized
University or
equivalent.
Desirable Qualifications
1. Candidates
with proven
experience
with the single
cell and bulk
transcriptome
data analysis
will be
preferred.
2: Candidates
with prior
experience
with
mammalian
cell culture
technique is
desirable.
Nature of Duty
Person hired
will be
responsible for
day-to-day
research
activities related
to molecular
biology and
biotechnology
work as
required for the
proposed
project. This
may also include
collection and
processing of
human tissue
samples from
collaborating
clinical centers.
The last date of application is 09.06.25 up to 9 AM
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